Cat With Blue Eyes

CAT DNA Testing

When you know your cat is affected, you can get help sooner.

How do I know if my Cat has the Mutation for PKD?

The only way to know for sure if your velvet-pawed pet is affected by the mutation for PKD is through DNA testing. Although there is no cure for affected cats, symptoms can be managed as directed by your veterinarian. This disease is most often seen in Persians.

PKD DNA Testing for Cats

Polycystic Kidney Disease (PKD) is an inherited autosomal dominant disorder characterized by the formation of cysts on the kidneys, PKD could lead to eventual renal failure and possible death. The PKD DNA test is available for the following cats breeds: Persians, Himalayans, Exotics, and crosses of these three.

PKD is dominant, therefore, heterozygotes (those possessing one copy of the mutation) will likely be clinically affected. When bred to genotypically-normal cats, heterozygotes are still likely to produce clinically affected offspring 50% of the time.

Tests:

 

  • Sterile DNA-collection swabs

  • Complete instructions

  • Postage-paid return envelope (if mailed in the U.S.)

You can also use a DIY kit to collect samples if you prefer.

Once testing is complete, we email a detailed DNA report showing the cat’s genotype for PKD.

The 3 possible genotypes include:

  • NN: 2 copies of the normal allele

  • NP Heterozygote: 1 normal copy and 1 copy of the PKD mutation

  • PP: 2 copies of the PKD mutation

Polycystic Kidney Disease Inheritance

The following table shows the expected distribution of progeny genotypes based on a mating where both parents have known genotypes.

Chart Legend:

N = Normal Allele
P = PKD Mutation
NN = 2 normal copies of the gene|
NP = 1 Normal copy, 1 copy of PKD mutation
PP = 2 copies of the PKD mutation

Test Highlights:

Name: Polycystic Kidney Disease (PKD)

DNA Samples: Collected at Home Using Cheek Swabs

Cost: $48 + S&H per Cat

Results: Within 10 Business Days after Receipt of Samples

cat-chart-Polycystic-Test.png

Pet Concierge Service

 

If you need assistance ordering, you're welcome to call us directly at 800.384.6DNA or email our team using the form on this page. We'll get back to you as soon as possible to help you place your order!

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